Identification of 4-Hydroxyheptachlorostyrene in Polar Bear Plasma and Its Binding Affinity to Transthyretin:  A Metabolite of Octachlorostyrene?

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Centre for Analytical and Environmental Chemistry, Department of Chemistry, Carleton University, 1125 Colonel By Drive, Ottawa, Ontario K1S 5B6, Canada, Department of Toxicology, Wageningen Agricultural University, Tuinlaan 5, 6703 HE Wageningen, The Netherlands, Wellington Laboratories Inc., 398 Laird Road, Guelph, Ontario, N1G 3X7 Canada, Research Institute of Toxicology, Utrecht University, P.O. Box 80.176, Yalelaan 2, Utrecht 3508 TD, The Netherlands, Institute for Environmental Studies, Free University of Amsterdam, De Boelelaan 1115, 1081 HV Amsterdam, The Netherlands, and Environment Canada, Canadian Wildlife Service, National Wildlife Research Centre (NWRC), 100 Gamelin Boulevard, Building 9, Hull, Québec, J8Y 1V9 Canada
C.D. Sandau, I.A.T.M. Meerts, R.J. Letcher, A. McAlees, B. Chittim, A. Brouwer, R.J. Norstrom. 2000. Identification of 4-hydroxy-heptachlorostyrene in polar bear plasma and its binding affinity to transthyretin: a metabolite of octachlorostyrene Environmental Science & Technology Vol. 34, No. 18, p. 3871-3877.

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